When Luis Sera, one of Saddler's researchers, tried to gave Leon a Master Plaga sample, the cult leader appeared and killed him, then took the sample, though Luis did give Leon a pill to suppress the control over the parasite.When Leon found him and tried to retrive Ashley, Saddler explained his plan to him and sent his occultists to attack him.He would then proceed to Infect the rest of the world with Las Plagas, allowing him world domination. He planned to infect her with one of the parasites, then send her back to her father for a ransom, so that she would infect the president as well, putting the U.S. President's daughter, Ashley Graham, a plan began forming in his mind.
Saddler then set out to take control of the world with his parasites and when Jack Krauser brought him the U.S. He also injected himself with a Master Plaga, so that he could mentally control the cultists. Infected people with the parasite by injecting them in egg form into the people, using this to turn all of the villagers into his cultists.Following this discovery, he established a large research complex and military base around ancient ruins on a nearby island to study the Plaga and over time genetically-engineered as many as three new species, which were significantly more difficult to be removed from the host Recessive Plagas (plaga strain that took over the host), Master Plaga (which endows the host ability to mutate at will as well as command over hosts of Recessive variant), and Queen Plaga that can asexually produced more eggs. However, the spores from the fossil still lived and when the miners breathed them in, Las Plagas developed within them many years later. Having obtained Salazar's backing and fortune, Saddler hired workers from the nearby village to mine the parasites, which had been fossilized and seemed dead.When he met Ramon Salazar, the castellan and ancestor of the Salazar family that had sealed the Las Plagas within their castle, he took an advantage of Ramon's isolation and loneliness, Saddler used his charisma to convince the eight castellan that his ancestor had committed a great sin by sealing the Las Plagas and stopping the Los Illuminados, leading to Salazar resolving to undo the seal placed on the Las Plagas parasites to atone for his ancestor's "sins.".Seeked and obtained materials for bio-weapons research along with resources to fund a paramilitary organisation, all of which is necessary to revive Los Illuminados cult.Visit here for more details: Osmund Saddler's Synopsis on the Villains Wiki.
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